
個人簡介:賈瑜倩,女,中共黨員🧑🏿💻,博士,校聘副教授。
2018年6月本科畢業於EON体育4動物藥學專業,2024年6月博士畢業於揚州大學獸醫EON4。同年11月作為引進人才入職EON体育4動物醫EON4。主要從事抗耐藥菌感染新策略的研究🙎🏽♀️,包括新型抗菌增效劑及基因轉移抑製劑的發現,耐藥新靶點的探究等🙁。目前在Journal of Pineal Research🧞♀️、Pharmacological Research等雜誌以第一作者發表SCI論文6篇,主持EON体育4引進人才科研專項1項,參與國家自然科學基金面上項目、江蘇省農業自主創新項目、江蘇省重點研究計劃等科研項目。
電子郵箱:jiayq2019@163.com
通訊地址:河北省保定市蓮池區樂凱南大街EON体育4西校區
研究方向:細菌耐藥性防控新策略研究
代表性論文🏇:
1. Yuqian Jia, Bingqing Yang, Jingru Shi, Dan Fang, Zhiqiang Wang, Yuan Liu. Melatonin prevents conjugative transfer of plasmid-mediated antibiotic resistance genes by disrupting proton motive force. Pharmacological Research. 2021, 175: 105978. IF=9.3.
2. Yuqian Jia, Bingqing Yang, et al. Melatonin protects intestinal against the inflammation and flora dysbiosis reshapes gut microbiota and remits the inflammation induced by megadose colistin. Journal of Pineal Research. 2024, 76(5): e12989. IF=8.3. (中科院一區)
3. Yuqian Jia, Zhiqiang Wang, Dan Fang, Bingqing Yang, Ruichao Li, Yuan Liu. Acetaminophen promotes horizontal transfer of plasmid-borne multiple antibiotic resistance genes. Science of the Total Environment. 2021, 8(782): 509-522. IF=9.736. (中科院一區TOP)
4. Yuan Liu#, Yuqian Jia#, Kangni Yang, Ziwen Tong, Jingru Shi, Ruichao Li, Xia Xiao, Wenkai Ren, Rüdiger Hardeland, Russel J. Reiter, Zhiqiang Wang. Melatonin overcomes MCR-mediated colistin resistance in Gram-negative pathogens. Theranostics. 2020, 10 (23): 10697-10711. IF=11.556. (中科院一區TOP)
5. Yuqian Jia, Zeyu Wang, Shuyao Zhu, Zhiqiang Wang, Yuan Liu. Disinfectants facilitate the transformation of exogenous antibiotic resistance genes via multiple pathways. Ecotoxicology and Environmental Safety. 2023, 253(9): 114678. IF=6.8. (中科院二區TOP)
6. Yuqian Jia, Zhiwan Zheng, Bingqing Yang, et al. A broad-spectrum horizontal transfer inhibitor blocks the transmission of antibiotic resistance. Transboundary and Emerging Diseases. 2024. 2024:13. IF=3.5. (中科院二區TOP)
7. Yuan Liu, Yuqian Jia, Kangni Yang, Ruichao Li, Xia Xiao, Kui Zhu, and Zhiqiang Wang. Metformin Restores Tetracyclines Susceptibility against Multidrug Resistant Bacteria. Advanced Science. 2020, 7(12):1902227. IF=15.1. (中科院一區TOP)
8. Yuan Liu, Yuqian Jia, Kangni Yang, Ruichao Li, Xia Xiao, Zhiqiang Wang. Anti-HIV agent azidothymidine decreases Tet(X)-mediated bacterial resistance to tigecycline in Escherichia coli. Communications Biology. 2020, 3(1):162. IF=5.9.
9. Yuan Liu, Kangni Yang, Yuqian Jia, Ruichao Li, Xia Xiao, Zhiqiang Wang. Gut microbiome alterations in high-fat-diet-fed mice are associated with antibiotic tolerance. Nature Microbiology. 2021, 6(7):874-884. IF=30.964. (中科院一區TOP)
參與發明專利
1.二甲雙胍和多西環素的組合物及其在製備細菌感染性疾病的藥物中的應用
(公開號: CN109432107A)。
2.褪黑素的用途(公開號: CN109999027A)。
3.疊氮胸苷的新用途(公開號: CN110368396A)。
4.雙硫侖在細菌感染疾病中的潛在應用(公開號: CN110974814A)。
5.黃酮類化合物在製備抑製耐藥質粒接合轉移的藥物中的應用(公開號: CN116492330A)🪢。