個人簡介👸：史萬玉👩🏿‍🍼，男，漢族🚢，博士，二級教授，博士生導師，EON体育4動物醫EON4/EON体育4平台副院長🤸🏿；河北省農業產業技術體系創新團隊中獸藥崗位專家、EON体育4太行學者、濟南市泉城學者🪢、EON体育4中獸醫學科帶頭人♻👉🏽；國家獸藥典委員🍁、農業農村部新獸藥評審專家🤸🏽、全國動物衛生標準化技術委員會委員；亞洲傳統獸醫與中獸醫學會副理事長➗、中國畜牧獸醫學會中獸醫學分會副理事長🧛🏽、中國獸醫協會中獸醫分會副理事長🏋🏿‍♂️、華北地區中獸醫研究會秘書長🥷🤯、河北省畜牧獸醫學會中獸醫學分會會長。近年來，取得科研成果18項，其中獲省級以上獎10項。在國際SCI期刊發表論文50多篇，核心期刊120多篇👨‍🎓，出版著作10余部，以第一發明人獲國家發明專利6項，獲國家新獸藥證書8個。目前主持的在研項目8項，其中，國家自然科學基金項目2項🎦，國家十四五重點研發計劃課題1項🧑‍🦲、河北省自然科學基金1項，河北省重點研發項目1項🏰🥣。曾先後赴臺灣、韓國、日本、美國、加拿大、西班牙、德國、法國、荷蘭、比利時等十多個國家和地區進行學術交流與業務考察。

電子郵箱：shiwanyu2010@126.com

通訊地址✊：保定市蓮池區樂凱南大街2596號

研究方向👨‍🏫：中藥藥理與中獸藥現代化🤹‍♂️；畜禽疾病防治與新型中獸藥創製

主講課程：《中獸醫學》、《中獸醫基礎理論》、《中獸醫案例分析》、《中獸醫診療技術》

一🕺🏿、科研獲獎：

1.“新型中獸藥的創製及其在雞健康養殖中的技術集成與應用”2020年獲河北省科技進步二等獎。

2．“奶牛主要疾病綜合防控關鍵技術研究與應用”，2013年獲河北省科技進步二等獎。

3.“黃芩等中藥及成分對母胎界面的免疫調節作用”，2010年獲河北省自然科學三等獎🚵🏿‍♂️。

4.“促孕保胎中藥防治母牛早期胚胎丟失的研究與應用”，2005年獲河北省科技進步三等獎🧑🏼‍🎤。

5.“中藥黃藿超微粉提高蛋雞生產性能與免疫力技術研究”，2007年獲河北省科技進步三等獎。

6.“健脾中藥對鴨胰液分泌的調節作用” 2007年獲河北省科技進步三等獎

7.“華北農區奶牛主要疾病防治技術與產業化示範”👼🏽，2007年獲河北省科技進步三等獎🥮。

8.“子宮自然殺傷細胞及相關細胞因子與母牛早期流產的相關性” 2003年獲河北省自然科學三等獎。

9.黃芪莖葉超微粉提高蛋雞免疫力和生產性能技術研究與應用（12150132A）👳🏼‍♀️，2016年獲石家莊市科技進步二等獎。

二、代表性論著🦖：

[1] Bao Yongzhan, Jing Cui, Shi Wanyu. Effects of Chinese herbal recipes on immunity in immunosuppressive mice[J]. African journal of traditional, complementary, and alternative medicines : AJTCAM,2012,9(4):548-552. （醫學四區🏉，IF:0.707）

[2] Cheng Jingjing, Li Qingyan, Shi Wanyu, Zhong Xiuhui. Effects of Huangqi Maxingshigan decoction on infectious laryngotracheitis in chickens[J]. Italian Journal of Animal Science, 2011, 10 (2):124-130.（農林科學三區🚶🏻‍➡️👷🏻‍♀️，IF:0.342）

[3] Yongzhan Bao, Wanyu Shi, Jianhua Qin. Effects of Chinese herbal formula "Kangshu I" on the blood heat shock protein (HSP70) and levels of some hormones in heat-stressed cows[J]. journal of medicinal plant research, 2011, 5(32):7061-7064.（醫學四區，IF:0.879）

[4] Wang Xiaodan,Ma Aituan, Shi Wanyu, Geng Meiying, Zhong Xiuhui,Zhao Yantao. Quercetin and Bornyl Acetate Regulate T-Lymphocyte Subsets and INF-γ/IL-4 Ratio In Utero in Pregnant Mice[J]. Evidence-based complementary and alternative medicine: eCAM,2011,2011:745262.（醫學三區，IF:4.774）

[5] Haifeng Hou, Qian Li, Wanyu Shi, Yongzhan Bao. Effects of Angelica polysaccharide on erythrocyte immunity and marrow hematopoiesis in chickens[J]. African Journal of Pharmacy & Pharmacology, 2012, 6(14):1037-1044. （醫學四區🥏，IF:0.839）

[6] Haifeng Hou,Yongzhan Bao,Qian Li,Wanyu Shi, ShiBing Su. Preparation of Blood-Deficient Model and Research of Angelica Polysaccharide on Enriching Blood in Chickens[J]. Evidence-Based Complementary and Alternative Medicine,2012,2012:965947. （醫學三區，IF:1.772）

[7] Chunhong Li, Yulong Dong, Haifeng Hou, Qian Li, Ruihua Zhang, Ruiling Qin, Zhonghao Li, Yongzhan Bao, Wanyu Shi. Effects of traditional Chinese herbal medicines on blood cell count and immunity in chickens[J]. African journal of pharmacy and pharmacology, 2013, 7(29):2081-2086. （醫學四區，IF:0.839）

[8] Chunhong Li, Wei Shi, Wanyu Shi. Mitochondrial genome sequence of Egyptian swift Rock Pigeon ( Columba livia breed Egyptian swift)[J]. Mitochondrial DNA,2014,26(3): 479-480.（生物三區，IF:1.6）

[9] Nan Xi, Jia Kang, Lijuan Hao, Ruijuan Li, Yongzhan Bao, Wanyu Shi. Effects of ultrafine powder of the stem and leaf of Astragalus on immunity in chickens[J]. Italian Journal of Animal Science, 2014, 13(1):3022.（農林科學三區，IF:0.718）

[10] Li Chunhong, Jin Shugang, Dong Yulong, Wang Li, Shi Wanyu. The complete mitochondrial genome of Rhodeus lighti (Cypriniformes: Cyprinidae): sequencing and analysis[J]. Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis,2016,27(3):2298-2299.（生物四區，IF:0.575）

[11] Chunhong Li,Yulong Dong,Zhong Hao Li,Ruihua Zhang,Ruiling Qin,Li Wang,Wanyu Shi. Effects of traditional Chinese herbal medicines on egg production, egg quality and antioxidant enzyme activities in aged laying hens[J]. Indian Journal of Animal Research,2017,51(2).（農林科學四區🧣，IF:0.201）

[12] Shuang Ma, Wanyu Shi, Xiaodan Wang,Pengyan Song, Xiuhui Zhong. Bisphenol A Exposure during Pregnancy Alters the Mortality and Levels of Reproductive Hormones and Genes in Offspring Mice[J]. BioMed Research International,2017,2017:3585809.（醫學三區，IF:2.583）

[13] Han Chao,Yang Jinkai,Song Pengyan,Wang Xiao,Shi Wanyu. Effects of Salvia miltiorrhiza Polysaccharides on Lipopolysaccharide-Induced Inflammatory Factor Release in RAW264.7 Cells[J]. Journal of interferon and cytokine research, 2018,38(1): 29-37.（醫學三區，IF：2.419）

[14] Shuang Ma,Ruiwen Li,Xincheng Gong, Wanyu Shi, Xiuhui Zhong. Lycopene reduces in utero bisphenol A exposure-induced mortality, benefits hormones, and development of reproductive organs in offspring mice[J]. Environmental Science and Pollution Research,2018,25(24): 24041-24051. （環境科學與生態學三區𓀅，IF:2.8）

[15] Tie Zhang,Jian Chen,Chunguang Wang,Wanyu Shi, Dinggang Li. The therapeutic effect of Yinhuangerchen mixture on Avian infectious laryngotracheitis[J]. Poultry Science,2018,97(8):2690-2697.（農林科學二區TOP✶，IF:2.216）

[16] Wang Xiao,Han Chao,Qin Jiaojiao,Wei Yuanyuan,Qian Xufeng,Bao Yongzhan,Shi Wanyu. Pretreatment with Salvia miltiorrhiza Polysaccharides Protects from Lipopolysaccharides/d-Galactosamine-Induced Liver Injury in Mice Through Inhibiting TLR4/MyD88 Signaling Pathway[J]. Journal of interferon and cytokine research,2019, 39(8):495-505.（醫學三區，IF:1.774）

[17] C.H. Li,Y.L. Dong,W.Y. Song,R.H. Zhang,J.L. Li,L. Wang, W.Y. Shi, T. Xu. Effects of traditional Chinese herbal medicines on blood parameters and antibody level in laying hens[J]. Indian Journal of Animal Research,2019,53(9):1194-1198.（農林科學四區，IF:0.437）

[18] Han Chao,Wei Yuanyuan,Wang Xiao,Ba Cuijing,Shi Wanyu*.Protective effect of Salvia miltiorrhiza polysaccharides on liver injury in chickens.[J]. Poultry science,2019,98(9): 3496–3503. （農林科學二區TOP🍠，IF:2.027）

[19] Chao Han,Yuanyuan Wei,Xiao Wang,Yuqing Cui,Yongzhan Bao,Wanyu Shi*. Salvia miltiorrhiza polysaccharides protect against lipopolysaccharide-induced liver injury by regulating NF-κb and Nrf2 pathway in mice[J]. Food and Agricultural Immunology,2019,30(1): 979–994.（農林科學二區, IF:2.568）

[20] Yuanyuan Wei,Chao Han,Yumeng Geng,Yuqing Cui,Yongzhan Bao,Wanyu Shi*,Xiuhui Zhong. Maternal exposure to bisphenol A during pregnancy interferes testis development of F1 male mice[J]. Environmental Science and Pollution Research,2019, 26(23):23491-23504. （環境科學與生態學三區， IF:2.914）

[21] Shilei Zhang,Jialu Bao,Xincheng Gong,Wanyu Shi*, Xiuhui Zhong. Hazards of bisphenol A —— blocks RNA splicing leading to abnormal testicular development in offspring male mice[J]. Chemosphere,2019,230: 432-439. （環境科學與生態學二區TOP⌚️，IF:5.108）

[22] Yuanyuan Wei,Shuying Li,Chao Han,Yongzhan Bao,Wanyu Shi*. Cuscuta chinensis flavonoids alleviate bisphenol A‐induced apoptosis of testicular cells in male mice offspring[J]. Andrologia,2019,51(11): e13427.（醫學四區，IF:1.84）

[23] Wei Yuanyuan,Han Chao,Li Shuying,Cui Yuqing,Bao Yongzhan, Shi Wanyu*. Cuscuta chinensis flavonoids down-regulate the DNA methylation of the H19/Igf2 imprinted control region and estrogen receptor alpha promoter of the testis in bisphenol A exposed mouse offspring.[J]. Food & function,2020,11(1):787-798.（農林科學一區TOP，IF:3.241）

[24] Yuanyuan Wei,Chao Han,Shuying Li,Yuqing Cui,Yongzhan Bao,Wanyu Shi*. Maternal exposure to bisphenol A during pregnancy interferes ovaries development of F1 female mice[J]. Theriogenology,2020,142:138-148.（農林科學二區TOP，IF:2.299）

[25] Chao Han,Yuanyuan Wei,Yuqing Cui,Yumemg Geng,Yongzhan Bao,Wanyu Shi*. Florfenicol induces oxidative stress and hepatocyte apoptosis in broilers via Nrf2 pathway[J]. Ecotoxicology and Environmental Safety,2020,191: 110239.（環境科學與生態學二區, IF:4.527）

[26] Chao Han, Yuanyuan Wei,Yumeng Geng,Yuqing Cui,Shuying Li,Yongzhan Bao,Wanyu Shi*. Bisphenol A in utero exposure induces ovary dysfunction in mice offspring and the ameliorating effects of Cuscuta chinensis flavonoids[J]. Environmental Science and Pollution Research,2020, 27(25):31357-31368.（環境科學與生態學三區☑️🫰🏼，IF:3.056）

[27] Chunhong Li, Yulong Dong, Ruihua Zhang, Li Wang, Wanyu Shi*, Tong Xu, Hongliang Zhang. Effects of Chinese Herbal Medicines on Lipid Metabolism and Immunity Function in Laying Hens[J]. Indian Journal of Animal Research, 2020, 54(10):1291-1295.（農林科學四區，IF:0.395）

[28] Wang Xiao,Han Chao,Cui Yuqing,Geng Yumeng,Wei Yuanyuan,Shi Wanyu*,Bao Yongzhan. Florfenicol induces renal toxicity in chicks by promoting oxidative stress and apoptosis[J]. Environmental science and pollution research, 2021, 28(1):936-946. （環境科學與生態學三區💆🏻‍♂️，IF:3.056）

[29] Xiao Wang,Chao Han,Yuqing Cui,Shuying Li,Guozhong Jin,Wanyu Shi*,Yongzhan Bao. Florfenicol causes excessive lipid peroxidation and apoptosis induced renal injury in broilers[J]. Ecotoxicology and Environmental Safety,2021,207: 111282. （環境科學與生態學二區🥖，IF:4.872）

[30] Cui YuQing,Han Chao,Li ShuYing,Geng YuMeng,Wei YuanYuan, Shi WanYu*,Bao YongZhan. High-throughput sequencing-based analysis of the intestinal microbiota of broiler chickens fed Compound Small Peptide of Chinese Medicine[J]. Poultry Science,2021, 100:100897.（農林科學二區TOP🤽🏽‍♀️，IF:2.659）

[31] Han Chao, Wang Xiao, Zhang Di, Wei Yuanyuan, Cui Yuqing, Shi Wanyu*, Bao Yongzhan. Synergistic use of florfenicol and Salvia miltiorrhiza polysaccharide can enhance immune responses in broilers[J]. Ecotoxicology and Environmental Safety,2021,210:111825. （環境科學與生態學二區🧺，IF:4.872）

[32]YumengGeng,ChunyuLu1,GuozhongJin,ShuyingLi,YuqingCui,ChaoHan,WanyuShi*,YongzhanBao Study on the mechanism of Salvia miltiorrhiza polysaccharides in relieving liver injury of broilers induced by florfenicol[J].. Environmental Science and Pollution Research, https://doi.org/10.1007 /s11356-021-15687-4, 13,August,2021（環境科學與生態學三區🕍，IF:3.056）

[33]ChaoHan, YuqingCui, YiweiGuo, DiZhang, XiaoWang,YumengGeng, WanyuShi,* and Yongzhan Bao. Proteome and transcriptome analysis revealed florfenicol via affected drug metabolism and lipid metabolism induce liver injuy of broilers[J]. 2021 Poultry Science100:101228 https://doi.org/10.1016/j.psj.2021.101228.（農林科學二區TOP，IF:2.659）

[34] Chunyu Lu，Lu Zhang📹，Yuqing Cui，Guozhong Jin，Yongzhan Bao🏋️‍♂️，Wanyu Shi*. Proteome and transcriptome explore the mechanism of Salvia miltiorrhiza polysaccharides to relieve forfenicol‑induced kidney injury in broilers Environmental Science and Pollution Research, https://doi.org/10.1007/s11356-022-19114-0,12, February,2022（環境科學與生態學三區🥾，IF:3.056）

[35] Xiao Wang , Wei Liu , Guozhong Jin, Zhanjun Wu , Di Zhang , Yongzhan Bao, Wanyu Shi* Salvia miltiorrhiza polysaccharides alleviates florfenicol induced kidney injury in chicks via inhibiting oxidative stress and apoptosis Ecotoxicology and Environmental Safety. 233 (2022) 113339 （環境科學與生態學二區🙊，IF:5.23）

[36] Wei Liu , Xiao Wang ,Ying Liu , Siyuan Fang , Zhanjun Wu , Chao Han , Wanyu Shi* ,Yongzhan Bao. Effects of early florfenicol exposure on glutathione signaling pathway and PPAR signaling pathway in chick liver. Ecotoxicology and Environmental Safety. 237 (2022) 113529（環境科學與生態學二區，IF:5.23）

[37]Wei Liu , Ying Liu , Siyuan Fang , Weiyu Yao , Xiao Wang ,Yongzhan Bao , Wanyu Shi*. Salvia miltiorrhiza polysaccharides alleviates florfenicol-induced liver metabolic disorder in chicks by regulating drug and amino acid metabolic signaling pathways[J]. Poultry Science (2022), doi: https://doi.org/10.1016/j.psj.2022.101989（農林科學二區TOP，IF:2.659）

[38]Cui Yuqing,Zhang Lu,Lu Chunyu,Dou Mengmeng,Jiao Yulan,Bao Yongzhan,Shi Wanyu*. Effects of compound small peptides of Chinese medicine on intestinal immunity and cecal intestinal flora in CTX immunosuppressed mice
[J]. Frontiers in Microbiology,2022,13.（生物學二區TOP）

[39] Zhang Di,Jin Guozhong,Liu Wei,Dou Mengmeng,Wang Xiao,Shi Wanyu*,Bao Yongzhan. Salvia miltiorrhiza polysaccharides ameliorates Staphylococcus aureus-induced mastitis in rats by inhibiting activation of the NF-κB and MAPK signaling pathways[J]. BMC Veterinary Research,2022,18(1).（農林科學二區）

[40] Xiao Wang , Wei Liu ,Ying Liu, Yulan Jiao , Chang Rong, Qi Liu, and Wanyu Shi*. Florfenicol induced renal inflammatory response and apoptosis via cell adhesion molecules signaling pathway [J]. Poultry Science 101:102152 https://doi.org/10.1016/j.psj.2022.102152（農林科學二區TOP🥨，IF:2.659）

[41] Xiao Wang, Wei Liu, Di Zhang, Yulan Jiao, Qianhui Zhao, Ying Liu,Wanyu Shi* ,Yongzhan Bao*. Salvia miltiorrhiza polysaccharides alleviate florfenicol-induced inflammation and oxidative stress in chick livers by regulating phagosome signaling pathway. Ecotoxicology and Environmental Safety. 249 (2023) 114428 (環境科學與生態學二區TOP🧖🏼‍♀️，IF:5.23）

[42] Qianhui Zhao , Ying Liu , Xiao Wang , Yixuan Zhu, Yulan Jiao, Yongzhan Bao, Wanyu Shi*.Cuscuta chinensis ffavonoids reducing oxidative stress of the improve sperm damage in bisphenol A exposed mice offspring. Ecotoxicology and Environmental Safety. 255 (2023) 114831 (環境科學與生態學二區TOP，IF:5.23）

[43] Yuqing Cui , Lu Zhang , Ying Liu , Wei Liu , Wanyu Shi* and Yongzhan Bao*. Compound small peptide of Chinese medicine alleviates cyclophosphamide induced immunosuppression in mice by Th17/Treg and jejunum intestinal flora[J]. Frontiers in Microbiology,2023,1039287.（生物學二區TOP）

[44]《中獸醫基礎理論》（農業農村部“十四五”規劃教材）💏，中國農業出版社🤹‍♂️👩🏻‍🍳，2024（待出版），主編

[45]《獸醫瘟病學》（農業農村部“十四五”規劃教材），中國農業出版社📸，2024（待出版），主編

[46]《中獸醫手冊》（第三版）.中國農業出版社，2010，副主編⛱。

[47]《中獸醫學實驗指導》（第三版），中國農業出版社𓀚，2016🧎‍♂️，5.副主編🟪。

[48]《獸醫中藥學》🌷，中國教育文化出版社，2006🧛🏽‍♂️，7副主編

[49]《中獸醫方劑學》中國教育文化出版社🐃，2006💇🏼‍♂️，2副主編

三、專利與新獸藥證書

[1]史萬玉,包永占,梁思嘉,秦建華,曹立輝,李瑞娟,鐘秀會,秦姣姣,梁銀聚. 用於治療豬支原體肺炎的中藥組合物及其應用. 專利號：ZL201810139678.6.

[2]史萬玉,曾勇慶,駱延波,陳寶江,吳傳文,劉在青,肖建森,郭麗華,鄭慶周. 一種母豬用復合中藥營養添加劑及其製備方法. 專利號：ZL201510240712.5.

[3]史萬玉,梁銀聚,秦建華,邵欣華,曹立輝,甄盼盼,李彩虹,包永占,鐘秀會,巴翠晶. 一種用於防治奶牛熱應激的中藥組方. 專利號：ZL201410694765.X.

[4]史萬玉,羅永祥,康建南,鐘秀會,黎明,文少懷,李林,康匯然,宋雪琴,胡智鵬. 一種治療奶牛乳房炎的灌註劑製備工藝. 專利號👐🏿：ZL201310223163.

[5]史萬玉,羅永祥,康建南,武力,戈軍珍,黎明,鐘秀會. 提高肉禽免疫力和生產性能的中藥口服液及其製備方法.專利號：ZL201210072257.9.

[6]史萬玉,羅永祥,康建南,歐日風,黎美,黎明,李林. 一種治療奶牛乳房炎的噴膜劑. 專利號：ZL201010294043.7.

[7]研發的國家三類新獸藥“芪楂口服液”（2015新獸藥證字19號），2015年4月獲國家新獸藥證書。

[8]研發的國家三類新獸藥“黃藿口服液”（2016新獸藥證字10號），2016年2月獲國家新獸藥證書。

[9]研發的國家四類新獸藥“玉屏風顆粒”（2016新獸藥證字17號），2016年3月獲國家新獸藥證書。

[10]研發的國家三類新獸藥“柴黃口服液”（2019新獸藥證字23號）🙇🏿‍♂️，2019年4月獲國家新獸藥證書♘。

[11]研發的國家三類新獸藥“銀黃二陳合劑”（2019新獸藥證字22號），2019年4月獲國家新獸藥證書👨🏽‍🔧。

[12]研發的國家三類新獸藥“金芩藍口服液”（2020新獸藥證字14號），2020年5月獲國家新獸藥證書。

[13]研發的國家三類新獸藥“合歡磁牡口服液”（2021新獸藥證字59號），2021年9月獲國家新獸藥證書。

[14]研發的國家三類新獸藥“蒲虎顆粒”（2023新獸藥證字22號），2023年4月獲國家新獸藥證書。

四👮、主要科研項目🎠：